Roland Nau Selected Research

Central Nervous System Infections (Central Nervous System Infection)

7/2022	Spatial and temporal variation of routine parameters: pitfalls in the cerebrospinal fluid analysis in central nervous system infections.
1/2021	Neural Injury and Repair in a Novel Neonatal Mouse Model of Listeria Monocytogenes Meningoencephalitis.
1/2021	Central nervous system infections and antimicrobial resistance: an evolving challenge.
1/2020	Intrathecal Antibacterial and Antifungal Therapies.
6/2018	Activin A increases phagocytosis of Escherichia coli K1 by primary murine microglial cells activated by toll-like receptor agonists.
1/2018	Pharmacokinetics and pharmacodynamics of antibiotics in central nervous system infections.
12/2014	Higher mortality and impaired elimination of bacteria in aged mice after intracerebral infection with E. coli are associated with an age-related decline of microglia and macrophage functions.
1/2014	Intraperitoneal prophylaxis with CpG oligodeoxynucleotides protects neutropenic mice against intracerebral Escherichia coli K1 infection.
6/2013	Toll-like receptor stimulation increases phagocytosis of Cryptococcus neoformans by microglial cells.
10/2010	Penetration of drugs through the blood-cerebrospinal fluid/blood-brain barrier for treatment of central nervous system infections.

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Roland Nau Research Topics

Disease

33	Infections 01/2022 - 08/2003
23	Bacterial Meningitis 01/2020 - 01/2002
22	Meningitis 04/2022 - 01/2002
19	Inflammation (Inflammations) 01/2021 - 01/2002
14	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 12/2017 - 12/2002
13	Central Nervous System Infections (Central Nervous System Infection) 07/2022 - 06/2003
8	Sepsis (Septicemia) 09/2021 - 07/2002
8	Bacterial Infections (Bacterial Infection) 01/2020 - 06/2007
5	Multiple Sclerosis 12/2019 - 09/2007
5	Pneumococcal Infections 01/2013 - 01/2003
4	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2019 - 08/2006
4	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2009 - 08/2005
4	Neuroblastoma 01/2009 - 12/2002
4	Escherichia coli Meningitis 12/2007 - 06/2003
3	Hypoxia (Hypoxemia) 01/2021 - 01/2017
3	Body Weight (Weight, Body) 01/2019 - 03/2005
2	Meningoencephalitis 01/2021 - 01/2015
2	Delirium 01/2021 - 06/2016
2	Cognitive Dysfunction 10/2020 - 09/2011
2	Brain Edema (Cerebral Edema) 01/2020 - 12/2017
2	Vitamin D Deficiency 01/2019 - 06/2014
2	Normal Pressure Hydrocephalus 11/2018 - 08/2016
2	Neuroinflammatory Diseases 01/2017 - 10/2009
2	Septic Shock (Toxic Shock Syndrome) 01/2017 - 01/2015
2	Encephalitis (Encephalitis, Rasmussen) 01/2017 - 08/2014
2	Seizures (Absence Seizure) 06/2016 - 12/2006
2	Brain Ischemia (Cerebral Ischemia) 01/2014 - 12/2006
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 06/2009 - 11/2007
2	Leukocytosis (Pleocytosis) 12/2007 - 08/2006
1	Polymyalgia Rheumatica (Rhizomelic Pseudopolyarthritis) 04/2022
1	Renal Insufficiency (Renal Failure) 11/2021
1	Malnutrition (Nutritional Deficiencies) 11/2021
1	Virus Diseases (Viral Diseases) 09/2021
1	Invasive Fungal Infections 07/2021
1	Chronic Obstructive Pulmonary Disease (COPD) 10/2020
1	Edema (Dropsy) 01/2020

Drug/Important Bio-Agent (IBA)

19	Anti-Bacterial Agents (Antibiotics)IBA 11/2021 - 01/2002
11	Proteins (Proteins, Gene)FDA Link 01/2016 - 07/2002
10	Ceftriaxone (Ceftriaxon)FDA LinkGeneric 01/2022 - 07/2002
10	Streptococcus pneumoniae plY proteinIBA 12/2017 - 11/2002
6	activin AIBA 06/2018 - 07/2003
6	Virulence Factors (Pathogenicity Factors)IBA 01/2013 - 11/2002
5	Activins (Activin)IBA 12/2012 - 05/2003
5	AcidsIBA 01/2012 - 01/2002
5	beta-LactamsIBA 07/2009 - 07/2002
5	Rifampin (Rifampicin)FDA LinkGeneric 07/2009 - 04/2003
5	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2007 - 06/2004
4	CytokinesIBA 09/2021 - 07/2012
4	Dexamethasone (Maxidex)FDA LinkGeneric 01/2020 - 01/2002
4	LipopolysaccharidesIBA 06/2015 - 09/2007
4	Toll-Like Receptors (Toll-Like Receptor)IBA 06/2014 - 06/2003
4	Adrenal Cortex Hormones (Corticosteroids)IBA 10/2013 - 01/2002
4	Lactic Acid (Lactate)FDA LinkGeneric 04/2012 - 08/2006
4	DNA (Deoxyribonucleic Acid)IBA 10/2009 - 01/2002
3	MelatoninIBA 01/2021 - 03/2005
3	Cholecalciferol (Vitamin D3)FDA Link 12/2019 - 01/2015
3	Interleukin-6 (Interleukin 6)IBA 01/2018 - 08/2006
3	palmidrolIBA 01/2018 - 06/2014
3	Toll-Like Receptor AgonistsIBA 06/2014 - 09/2007
3	CytosineIBA 01/2014 - 09/2007
3	Neuroprotective AgentsIBA 01/2014 - 11/2006
3	Protein Synthesis InhibitorsIBA 01/2005 - 01/2002
3	Clindamycin (Cleocin)FDA LinkGeneric 12/2004 - 07/2002
2	AnticoagulantsIBA 11/2021 - 01/2018
2	Pharmaceutical PreparationsIBA 07/2021 - 10/2010
2	LactamsIBA 01/2021 - 01/2002
2	Neurotransmitter Agents (Neurotransmitter)IBA 01/2021 - 01/2017
2	Poly I-CIBA 01/2020 - 09/2010
2	CalciumIBA 01/2019 - 06/2009
2	LipidsIBA 01/2018 - 02/2012
2	ChemokinesIBA 01/2018 - 12/2014
2	tau Proteins (tau Protein)IBA 08/2016 - 01/2011
2	OligodeoxyribonucleotidesIBA 06/2014 - 01/2014
2	Anti-Infective Agents (Microbicides)IBA 01/2013 - 12/2004
2	FollistatinIBA 12/2012 - 05/2003
2	AntibodiesIBA 04/2012 - 01/2003
2	Bromodeoxyuridine (BrdU)IBA 06/2009 - 08/2003
2	Toll-Like Receptor 2IBA 11/2007 - 08/2006
2	Hemolysin Proteins (Hemolysins)IBA 11/2007 - 04/2005
2	AntioxidantsIBA 11/2007 - 11/2006
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 09/2007 - 07/2005
2	Messenger RNA (mRNA)IBA 09/2005 - 06/2003
2	EndotoxinsIBA 04/2005 - 01/2002
1	AntigensIBA 07/2022
1	Voriconazole (Vfend)FDA LinkGeneric 04/2022
1	InterferonsIBA 09/2021
1	AzolesIBA 07/2021
1	Caspase 3 (Caspase-3)IBA 01/2021
1	Dexmedetomidine FDA Link 01/2021
1	Chemokine CCL5IBA 01/2020
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020
1	Antimicrobial Cationic PeptidesIBA 01/2019
1	Vitamin D FDA LinkGeneric 01/2019
1	Antimicrobial PeptidesIBA 01/2019
1	Anesthetics (Anesthetic Agents)IBA 01/2019

Therapy/Procedure

21	Therapeutics 01/2021 - 01/2002
2	Intraperitoneal Injections 01/2020 - 12/2012
1	Long-Term Care 11/2021
1	Dentures 07/2021
1	Nebulizers and Vaporizers (Inhaler) 10/2020